Description

3-Borono-5-Fluoro-4-Methylbenzoic Acid is a high-value, multi-functional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, combining a boronic acid group with fluorine and carboxylic acid functionalities, makes it an indispensable reagent for constructing complex molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel biaryl compounds with potential therapeutic activity.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require specific fluorine and boronic acid motifs for bioactivity.
• Material Science: Serves as a monomer or functionalization agent in the creation of advanced polymers, metal-organic frameworks (MOFs), and liquid crystals.
• Chemical Biology & Proteomics: Utilized as a probe or linker in the study of biological processes and for the immobilization of biomolecules.
• Diagnostic Reagent Synthesis: Employed in the production of specialized reagents and contrast agents for medical imaging and diagnostic assays.
• Organic Electronics: Acts as a building block for electron-transport materials and other components in OLEDs and organic photovoltaics.

Basic Information

Product Name	3-Borono-5-Fluoro-4-Methylbenzoic Acid
CAS No.	917223-87-1
Molecular Formula	C8H8BFO4
Molecular Weight	197.96 g/mol
Synonyms	5-Fluoro-4-methyl-3-boronobenzoic acid; (3-Carboxy-5-fluoro-4-methylphenyl)boronic acid; 3-Borono-5-fluoro-p-toluic acid; Benzoic acid, 3-borono-5-fluoro-4-methyl-; B-(3-Carboxy-5-fluoro-4-methylphenyl)boronic acid; 5-Fluoro-4-methyl-1,3-benzoxaborole-7-carboxylic acid (tautomeric form)
EINECS	Contact for details

Quality Control

Every batch of 3-Borono-5-Fluoro-4-Methylbenzoic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as purity (by HPLC/NMR), identity confirmation, and impurity profiles. Our quality commitment supports compliance in cGMP and ISO 9001 environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.