Description

3-[2-Chloro-3-(Trifluoromethyl)Phenyl]Propionic Acid is a high-value fluorinated aromatic building block essential for advanced organic synthesis. This compound matters because its unique structure, featuring both chloro and trifluoromethyl substituents, enables the precise modulation of physicochemical properties in target molecules. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting inflammation, CNS disorders, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances bioavailability and metabolic stability.
• Liquid Crystal Materials: Serves as a precursor for fluorinated mesogens in the production of advanced display technologies.
• Organic Electronic Materials: Employed in the synthesis of specialized monomers and polymers for organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Research & Development: A versatile reagent for exploring new synthetic methodologies and creating complex molecular architectures in academic and industrial labs.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke intermediates under cGMP or research-grade conditions.

Basic Information

Product Name	3-[2-Chloro-3-(Trifluoromethyl)Phenyl]Propionic Acid
CAS No.	916420-76-3
Molecular Formula	C10H8ClF3O2
Molecular Weight	252.62 g/mol
Synonyms	2-Chloro-α,α,α-trifluoro-m-toluic acid, β-propionic acid; 3-(2-Chloro-3-(trifluoromethyl)phenyl)propanoic acid; 2-Chloro-3-trifluoromethylhydrocinnamic acid; 916420-76-3; β-(2-Chloro-3-trifluoromethylphenyl)propionic acid; m-Toluic acid, 2-chloro-α,α,α-trifluoro-, β-propionic acid derivative
EINECS	Contact for details

Quality Control

Our 3-[2-Chloro-3-(Trifluoromethyl)Phenyl]Propionic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring research-grade to cGMP-compliant materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.