Description

Pentafluorophenyl 4-(1-Methyl-1H-Pyrazol-3-Yl)Benzoate is a specialized fluorinated aromatic ester compound that serves as a high-value synthetic intermediate. Its molecular architecture, featuring a pentafluorophenyl ester group linked to a pyrazole-substituted benzoate, makes it a critical building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and advanced materials sectors for applications in medicinal chemistry, agrochemical research, and the development of functional polymers.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting kinase inhibition and other therapeutic areas.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its unique fluorinated structure for enhanced bioactivity and stability.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Acts as a reactive handle in activity-based protein profiling (ABPP) and the synthesis of biochemical probes due to the reactivity of the pentafluorophenyl ester group.
• Organic Synthesis: A versatile reagent for peptide coupling and esterification reactions under mild conditions, facilitating complex molecule assembly.
• Fluorine Chemistry Research: An important compound for studying the effects of perfluorinated aryl groups on molecular reactivity and physical properties.

Basic Information

Product Name	Pentafluorophenyl 4-(1-Methyl-1H-Pyrazol-3-Yl)Benzoate
CAS No.	915707-42-5
Molecular Formula	C18H10F5N2O2
Molecular Weight	381.28 g/mol
Synonyms	4-(1-Methyl-1H-pyrazol-3-yl)benzoic acid pentafluorophenyl ester; Pentafluorophenyl 4-(1-methyl-1H-pyrazol-3-yl)benzoate; Benzoic acid, 4-(1-methyl-1H-pyrazol-3-yl)-, 2,3,4,5,6-pentafluorophenyl ester; 2,3,4,5,6-Pentafluorophenyl 4-(1-methyl-1H-pyrazol-3-yl)benzoate; PFP 4-(1-Methyl-1H-pyrazol-3-yl)benzoate
EINECS	Contact for details

Quality Control

Every batch of Pentafluorophenyl 4-(1-Methyl-1H-Pyrazol-3-Yl)Benzoate is manufactured and analyzed under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards for research and process chemistry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.