Description

3,5-Difluoro-4-Difluoromethoxy-Benzeneboronic Acid is a high-purity, multi-fluorinated boronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and advanced materials where the introduction of fluorine atoms is required to modulate biological activity, metabolic stability, and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key synthon for constructing fluorinated active pharmaceutical ingredients (APIs) and drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of novel fluorinated pesticides, herbicides, and fungicides to enhance efficacy and environmental profile.
• Material Science: Serves as a monomer or precursor for synthesizing specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating compound libraries.
• PET (Positron Emission Tomography) Tracer Development: Potential use in synthesizing fluorinated radiotracers for medical imaging applications.

Basic Information

Product Name	3,5-Difluoro-4-Difluoromethoxy-Benzeneboronic Acid
CAS No.	915401-97-7
Molecular Formula	C7H5BF4O3
Molecular Weight	219.92 g/mol
Synonyms	4-(Difluoromethoxy)-3,5-difluorobenzeneboronic Acid; (4-(Difluoromethoxy)-3,5-difluorophenyl)boronic Acid; 3,5-Difluoro-4-(difluoromethoxy)phenylboronic Acid; B-[4-(Difluoromethoxy)-3,5-difluorophenyl]boronic Acid; 915401-97-7; AKOS005258030; FT-0774508; A839058; SCHEMBL21842427; DTXSID70731892
EINECS	Contact for details

Quality Control

Our 3,5-Difluoro-4-Difluoromethoxy-Benzeneboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting the exact specifications for your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.