Description

((2R,3S,4R,5R)-5-(6-(((S)-2,3-Dihydro-1H-Inden-1-Yl)Amino)-9H-Purin-9-Yl)-3,4-Dihydroxytetrahydrofuran-2-Yl)Methyl Sulfamate is a high-purity, nucleoside-based chemical building block with a complex, defined stereochemistry. This compound is of significant interest for advanced pharmaceutical research and development, particularly in the field of targeted therapeutics. It is primarily utilized by R&D scientists and process chemists in the pharmaceutical and biotechnology industries for the synthesis of novel drug candidates and as a key reference standard.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel nucleoside analog drugs targeting specific enzymes or receptors.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate metabolic pathways and mechanisms of action.
• Antiviral Drug Development: Potential application in the research and development of antiviral agents due to its modified nucleoside structure.
• Oncology Research: Investigated for use in creating targeted cancer therapies that interfere with DNA/RNA synthesis in malignant cells.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Process Chemistry: Used in route scouting and optimization for the scalable production of complex active pharmaceutical ingredients (APIs).

Basic Information

Product Name	((2R,3S,4R,5R)-5-(6-(((S)-2,3-Dihydro-1H-Inden-1-Yl)Amino)-9H-Purin-9-Yl)-3,4-Dihydroxytetrahydrofuran-2-Yl)Methyl Sulfamate
CAS No.	905578-77-0
Molecular Formula	C20H22N6O6S
Molecular Weight	474.49 g/mol
Synonyms	9-[(2R,3S,4R,5R)-5-[(Sulfamoyloxy)methyl]-3,4-dihydroxyoxolan-2-yl]-6-[[(1S)-2,3-dihydro-1H-inden-1-yl]amino]purine; Sulfamic acid, N-[[(2R,3S,4R,5R)-5-[6-[[(1S)-2,3-dihydro-1H-inden-1-yl]amino]-9H-purin-9-yl]-3,4-dihydroxy-2-tetrahydrofuranyl]methyl]-; (2R,3S,4R,5R)-5-(6-(((S)-2,3-Dihydro-1H-Inden-1-yl)amino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl sulfamate; Modified Adenosine Sulfamate Derivative; Indanyl-amino Purine Nucleoside Sulfamate
EINECS	Contact for details

Quality Control

Our ((2R,3S,4R,5R)-5-(6-(((S)-2,3-Dihydro-1H-Inden-1-Yl)Amino)-9H-Purin-9-Yl)-3,4-Dihydroxytetrahydrofuran-2-Yl)Methyl Sulfamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.