Description

2-Fluoro-6-Picoline-5-Boronic Acid is a high-value organoboron building block, specifically a heterocyclic boronic acid derivative. Its core value proposition lies in enabling precise Suzuki-Miyaura cross-coupling reactions, a cornerstone of modern synthetic chemistry for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to introduce the 2-fluoro-6-picoline moiety into target structures.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides requiring specific fluorinated heterocyclic structures.
• Ligand Precursor: Serves as a starting material for creating specialized ligands used in catalysis and material science.
• Chemical Research: A versatile reagent in academic and industrial R&D for exploring new chemical spaces and reaction methodologies via cross-coupling.
• Material Science: Potential monomer or building block for creating functional polymers and organic electronic materials.

Basic Information

Product Name	2-Fluoro-6-Picoline-5-Boronic Acid
CAS No.	904326-91-6
Molecular Formula	C7H7BFNO2
Molecular Weight	166.95 g/mol
Synonyms	(6-Fluoro-2-methylpyridin-3-yl)boronic acid; 2-Fluoro-6-methylpyridine-3-boronic acid; 3-Borono-2-fluoro-6-picoline; 2-Fluoro-6-methyl-3-pyridineboronic acid; 2-Fluoro-6-methyl-3-pyridinylboronic acid; 2-Fluoro-6-methylpyridin-3-ylboronic acid; 904326-91-6; 2-Fluoro-6-picoline-5-boronic acid pinacol ester (related ester)
EINECS	Contact for details

Quality Control

Our 2-Fluoro-6-Picoline-5-Boronic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.