Description

n-Methyl-D-Prolinol is a chiral pyrrolidine derivative and a valuable building block in asymmetric synthesis. This compound matters as a key intermediate for the production of advanced pharmaceutical ingredients and fine chemicals, enabling the creation of molecules with high stereochemical purity. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new drugs, catalysts, and functional materials.

Application

• Pharmaceutical Intermediate: A crucial chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) drugs and other therapeutics requiring specific stereochemistry.
• Asymmetric Catalyst Ligand: Serves as a precursor for chiral ligands used in metal-catalyzed asymmetric reactions, such as hydrogenation and C-C bond formation, to produce enantiomerically pure compounds.
• Agrochemical Synthesis: Used in the research and development of chiral pesticides and herbicides where biological activity is stereospecific.
• Fine Chemical Building Block: Employed in the synthesis of complex natural products, flavors, fragrances, and other high-value specialty chemicals.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	n-Methyl-D-Prolinol
CAS No.	99494-01-6
Molecular Formula	C6H13NO
Molecular Weight	115.17 g/mol
Synonyms	(R)-1-Methyl-2-pyrrolidinemethanol; (R)-(-)-1-Methyl-2-pyrrolidinemethanol; D-(-)-1-Methyl-2-pyrrolidinemethanol; (R)-1-Methylpyrrolidine-2-methanol; (2R)-1-Methylpyrrolidine-2-methanol; (R)-N-Methylprolinol; (R)-N-Methyl-2-pyrrolidinemethanol
EINECS	Contact for details

Quality Control

Our n-Methyl-D-Prolinol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.