Description

Ganglioside Gm3 Lactone is a specialized glycosphingolipid derivative, a lactonized form of the monosialylated ganglioside GM3. This compound is a critical biochemical tool and a key intermediate in glycobiology research, valued for its role in studying cell membrane dynamics and carbohydrate-protein interactions. It is primarily utilized by research institutions and pharmaceutical developers focused on neuroscience, oncology, and metabolic disease studies, where understanding ganglioside function and metabolism is paramount.

Application

• Biochemical Research: As a high-purity standard or substrate for enzymatic studies involving glycosidases and sialidases.
• Glycobiology Studies: Investigating the structure, function, and metabolism of gangliosides in cellular signaling pathways.
• Neuroscience Research: Exploring the role of ganglioside derivatives in neural development, function, and in models of neurological disorders.
• Pharmaceutical Development: Serving as a reference compound or intermediate in the development of therapeutic agents targeting glycosphingolipid-related diseases.
• Diagnostic Reagent Manufacturing: Potential use in the formulation of specialized reagents for diagnostic assays.
• Academic & Industrial R&D: Fundamental research in lipidomics and membrane biology within university and corporate laboratories.

Basic Information

Product Name	Ganglioside Gm3 Lactone
CAS No.	99477-47-1
Molecular Formula	C73H129N3O31
Molecular Weight	1568.8 g/mol
Synonyms	GM3 Lactone; II3Neu5Ac-LacCer Lactone; Monosialyl-lactosylceramide Lactone; Lactosylceramide GM3 Lactone; N-Acetylneuraminosyl-lactosylceramide Lactone; Ganglioside LM1 Lactone (related); α-Neu5Ac-(2→3)-β-D-Gal-(1→4)-β-D-Glc-Ceramide Lactone
EINECS	Contact for details

Quality Control

Our Ganglioside Gm3 Lactone is produced under stringent quality protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is characterized using advanced analytical techniques including HPLC and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurities is provided with every shipment, supporting traceability and compliance with internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Solubility	Soluble in chloroform/methanol mixtures

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.