Description

Cyclopropanecarboxylic Acid, 2-Ethenyl-, Methyl Ester, (1R,2S)- (9Ci) is a high-purity, stereochemically defined cyclopropane derivative, a class of compounds prized for their unique structural rigidity and reactivity. This specific enantiomer is a critical chiral building block in advanced organic synthesis, enabling the construction of complex molecules with precise three-dimensional architecture. It is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, where stereochemical control is paramount for efficacy and safety.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug discovery and development.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the cyclopropane ring contributes to biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to induce high enantioselectivity.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials that require rigid, strained molecular components.
• Flavor and Fragrance Chemistry: Acts as an intermediate for creating complex, stereospecific aroma molecules.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic chemistry and the exploration of new cyclopropanation reactions.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 2-Ethenyl-, Methyl Ester, (1R,2S)- (9Ci)
CAS No.	99438-14-9
Molecular Formula	C7H10O2
Molecular Weight	126.15 g/mol
Synonyms	(1R,2S)-2-Vinylcyclopropanecarboxylic acid methyl ester; Methyl (1R,2S)-2-vinylcyclopropanecarboxylate; (1R,2S)-Methyl 2-vinylcyclopropanecarboxylate; (-)-(1R,2S)-2-Vinylcyclopropanecarboxylic acid methyl ester; (1R-cis)-2-Ethenylcyclopropanecarboxylic Acid Methyl Ester; Chiral vinylcyclopropane ester; Cyclopropane carboxylic acid, 2-ethenyl-, methyl ester, (1R,2S)-
EINECS	Contact for details

Quality Control

Our production of Cyclopropanecarboxylic Acid, 2-Ethenyl-, Methyl Ester, (1R,2S)- (9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure high chemical and stereochemical purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.