Description

(3R,4R)-(+)-Bis(Diphenylphosphino)Pyrrolidine CAS NO 99135-90-7 is a high-purity, chiral bisphosphine ligand widely used in asymmetric catalysis. This compound matters because it enables the precise control of stereochemistry in critical synthetic transformations, leading to higher yields and enantiomeric purity of target molecules. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries who develop and manufacture chiral active ingredients.

Application

• As a chiral ligand in asymmetric hydrogenation reactions for the synthesis of pharmaceutical intermediates.
• Catalyst component in asymmetric C-C bond formation reactions, such as cross-coupling and allylic alkylation.
• Key reagent for the preparation of enantiomerically pure compounds in medicinal chemistry research.
• Use in asymmetric isomerization and hydroformylation processes.
• Development of novel transition metal catalysts for academic and industrial research.
• Production of chiral flavors, fragrances, and agrochemicals.

Basic Information

Product Name	(3R,4R)-(+)-Bis(Diphenylphosphino)Pyrrolidine
CAS No.	99135-90-7
Molecular Formula	C32H29P2N
Molecular Weight	489.53 g/mol
Synonyms	(3R,4R)-(+)-Bis(Diphenylphosphino)Pyrrolidine; (R,R)-Bis(diphenylphosphino)pyrrolidine; (R,R)-BPP; (3R,4R)-BPP; (R,R)-2,5-Bis(diphenylphosphino)pyrrolidine; (R,R)-DIPAMP Analogue; (R,R)-BDPP; (3R,4R)-1,4-Bis(diphenylphosphino)pyrrolidine
EINECS	Contact for details

Quality Control

Our (3R,4R)-(+)-Bis(Diphenylphosphino)Pyrrolidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity. Certificates of Analysis (COA) detailing purity, specific rotation, and identity are provided with every shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store under an inert atmosphere (argon or nitrogen) at 2-8°C. The product is easily oxidized and should be handled in a glovebox or under a positive pressure of inert gas to maintain purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (ee)	≥ 99.0%
Specific Rotation [α]D20	+250° to +270° (c = 1 in CHCl3)
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.