Description

2-Pyrrolidinemethanol, 3-Hydroxy-, Hydrochloride, (2R,3S)- is a high-purity chiral building block and pharmaceutical intermediate of significant commercial interest. This compound is valued for its stereochemically defined structure, which is crucial for the synthesis of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel therapeutic agents and advanced materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of various APIs, particularly in neurological and cardiovascular drug research.
• Asymmetric Catalysis: Used as a precursor or ligand in the development of chiral catalysts for stereoselective synthesis.
• Agrochemical Research: Serves as a building block for novel, optically active pesticides and herbicides.
• Fine Chemical Synthesis: Employed in the production of complex, high-value specialty chemicals and flavors/fragrances.
• Academic & R&D: Utilized in chemical research for studying reaction mechanisms and developing new synthetic methodologies.
• Bioconjugation & Linker Chemistry: Potential use in creating drug conjugates or biochemical probes due to its functional groups.

Basic Information

Product Name	2-Pyrrolidinemethanol, 3-Hydroxy-, Hydrochloride, (2R,3S)-
CAS No.	98900-30-2
Molecular Formula	C5H12ClNO2
Molecular Weight	153.61 g/mol
Synonyms	(2R,3S)-3-Hydroxy-2-pyrrolidinemethanol hydrochloride; (2R,3S)-3-Hydroxypyrrolidine-2-methanol hydrochloride; (2R,3S)-2-(Hydroxymethyl)-3-pyrrolidinol hydrochloride; cis-3-Hydroxy-2-pyrrolidinemethanol hydrochloride; (2R,3S)-2-Pyrrolidinemethanol, 3-hydroxy-, hydrochloride; L-threo-3-Hydroxy-2-pyrrolidinemethanol hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Pyrrolidinemethanol, 3-Hydroxy-, Hydrochloride, (2R,3S)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and specific impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.