Description

Reboxetine Methanesulfonate is a high-purity pharmaceutical intermediate and active ingredient. This compound is the methanesulfonate salt of Reboxetine, a selective norepinephrine reuptake inhibitor (NRI), which is critical for ensuring consistent bioavailability and stability in final formulations. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in the development and production of central nervous system (CNS) therapeutics, particularly for the treatment of depressive disorders.

Application

• Pharmaceutical Active Ingredient: Primary use as the active pharmaceutical ingredient (API) in antidepressant formulations.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in pharmaceutical labs.
• Clinical Research: Used in preclinical and clinical studies investigating the efficacy and pharmacokinetics of norepinephrine reuptake inhibitors.
• Process Development: A key intermediate in the synthesis and scale-up of Reboxetine-based drug products.
• Academic Research: Employed in biochemical and pharmacological research to study neurotransmitter reuptake mechanisms.

Basic Information

Product Name	Reboxetine Methanesulfonate
CAS No.	98769-82-5
Molecular Formula	C19H23NO3 • CH4O3S
Molecular Weight	409.50 g/mol
Synonyms	Reboxetine Mesylate; (R*,R*)-2-[(2-Ethoxyphenoxy)phenylmethyl]morpholine methanesulfonate; FCE 20124; FCE-20124; Reboxetine Methanesulphonate; Reboxetine Metilsulfate; Reboxetinium Methanesulfonate
EINECS	Contact for details

Quality Control

Our Reboxetine Methanesulfonate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by spectroscopic methods, to ensure it meets stringent pharmaceutical-grade specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with relevant guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.