Description

Reboxetine is a selective norepinephrine reuptake inhibitor (NRI) with the CAS registry number 98769-81-4. This compound is of significant interest in the pharmaceutical industry for its role as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs) targeting central nervous system disorders. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of antidepressant and neuropharmacological agents.

Application

• Primary intermediate in the synthesis of the antidepressant drug, Reboxetine.
• Key building block for research and development of novel norepinephrine reuptake inhibitors.
• Reference standard for analytical method development and quality control in pharmaceutical laboratories.
• Starting material for the preparation of deuterated or isotopically labeled analogs for metabolic studies.
• Used in academic and industrial research investigating the pharmacology of neurotransmitter transporters.
• Critical component in process chemistry for scaling up API manufacturing under GMP conditions.

Basic Information

Product Name	Reboxetine
CAS No.	98769-81-4
Molecular Formula	C19H23NO3
Molecular Weight	313.39 g/mol
Synonyms	Reboxetine; (RS)-2-[(RS)-α-(2-Ethoxyphenoxy)benzyl]morpholine; FCE 20124; FCE-20124; Edronax (brand name); Norepinephrine Reuptake Inhibitor; (R*,S*)-2-[(α-(2-Ethoxyphenoxy)benzyl]morpholine
EINECS	Contact for details

Quality Control

Our Reboxetine is manufactured under strict quality management systems to ensure high purity and batch-to-batch consistency. The product is tested against rigorous in-house specifications, which typically include identification, assay, and impurity profile analysis. A Certificate of Analysis (COA) detailing the results for each batch is available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.