Description

Collagenase Chromophore Substrate Test Substance (For Quantitative Collagenase-Determination) is a specialized biochemical reagent designed for the accurate quantification of collagenase enzyme activity. This high-purity substrate is critical for ensuring the reliability and reproducibility of enzymatic assays in research and quality control environments. It is primarily utilized by biopharmaceutical manufacturers, contract research organizations (CROs), and academic laboratories involved in collagenase-related studies, tissue dissociation protocols, and therapeutic enzyme characterization.

Application

• Quantitative Enzymatic Assays: Primary substrate for the precise spectrophotometric determination of collagenase activity in research and industrial samples.
• Biopharmaceutical Quality Control: Used in the potency testing and batch release of therapeutic collagenase products, such as those used in wound debridement and Dupuytren's contracture treatment.
• Biochemical Research: Essential tool for studying collagenase kinetics, inhibition mechanisms, and enzyme specificity in academic and industrial R&D.
• Tissue Engineering & Cell Culture: Supports method development and validation for tissue dissociation protocols where controlled collagenase activity is paramount.
• Diagnostic Reagent Manufacturing: A key component in the formulation of diagnostic kits for measuring collagenase levels in clinical or research settings.
• Method Validation & Standardization: Serves as a reference standard to calibrate equipment and validate new analytical methods for collagenase detection.

Basic Information

Product Name	Collagenase Chromophore Substrate Test Substance (For Quantitative Collagenase-Determination)
CAS No.	98640-71-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Collagenase Substrate; Chromogenic Collagenase Substrate; Collagenase Chromogenic Substrate; 4-Phenylazobenzyloxycarbonyl-Pro-Leu-Gly-Pro-D-Arg; PZ-Pro-Leu-Gly-Pro-D-Arg; PZ-Collagenase Substrate; Synthetic Collagenase Substrate; Azocoll-type Substrate Analog
EINECS	Contact for details

Quality Control

Our Collagenase Chromophore Substrate Test Substance is manufactured under strict quality management systems to ensure batch-to-batch consistency and high performance in sensitive enzymatic assays. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and functional activity. We adhere to relevant industry guidelines for biochemical reagents to support our customers' compliance with GMP, ISO, and other regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	Yellow to orange powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Functional Activity	Conforms to reference standard
Solubility	Soluble in suitable assay buffers (e.g., DMSO, aqueous buffers)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.