Description

(1R,2R)-2-((R)-1-Phenylethylamino)Cyclohexanol is a high-purity chiral amine derivative, specifically a diastereomerically pure cyclohexanolamine. This compound serves as a critical chiral building block and resolving agent in asymmetric synthesis, valued for its ability to impart stereochemical control. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals requiring precise stereochemistry.

Application

• Chiral Auxiliary/Resolving Agent: Employed in the resolution of racemic mixtures of acids and other compounds via diastereomeric salt formation.
• Pharmaceutical Intermediate: A key precursor in the synthesis of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Catalyst Ligand Precursor: Used to synthesize chiral ligands for asymmetric catalysis, including hydrogenation and transfer hydrogenation reactions.
• Agrochemical Synthesis: Integral to the production of enantiopure herbicides, fungicides, and plant growth regulators.
• Academic & Process Chemistry Research: A valuable reagent for methodological development in stereoselective synthesis and scale-up studies.
• Fine Chemical Production: Used in the manufacture of specialty chemicals where optical purity is a critical quality attribute.

Basic Information

Product Name	(1R,2R)-2-((R)-1-Phenylethylamino)Cyclohexanol
CAS No.	98462-58-9
Molecular Formula	C14H21NO
Molecular Weight	219.33 g/mol
Synonyms	(1R,2R)-2-[(1R)-1-Phenylethylamino]cyclohexanol; (1R,2R)-(-)-2-((R)-1-Phenylethylamino)cyclohexanol; (1R,2R)-2-[(R)-α-Methylbenzylamino]cyclohexanol; (-)-trans-2-[(R)-1-Phenylethylamino]cyclohexanol; (1R,2R)-2-[(R)-1-Phenylethylamino]-1-cyclohexanol; (1R,2R)-N-[(R)-1-Phenylethyl]cyclohexane-1,2-diamine derivative; Chiral Cyclohexanolamine Derivative
EINECS	Contact for details

Quality Control

Our (1R,2R)-2-((R)-1-Phenylethylamino)Cyclohexanol is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) and diastereomeric excess (de) verification, to ensure it meets the high-purity standards required for synthetic applications. A detailed Certificate of Analysis (COA) providing full specification data is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Diastereomeric Purity (HPLC)	≥ 99.0% de
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.