Description

8(S)-Hete CAS NO 98462-03-4 is a high-purity, stereospecific hydroxy eicosatetraenoic acid derivative, a significant bioactive lipid mediator. This compound is valued for its role as a key intermediate and reference standard in advanced biochemical and pharmacological research. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for studying inflammation pathways, metabolic processes, and developing novel therapeutic agents.

Application

• Biochemical Research: Used as a critical reference standard and analytical reagent in lipidomics and eicosanoid research.
• Pharmaceutical Development: Serves as a key intermediate and active pharmaceutical ingredient (API) precursor in the synthesis of novel anti-inflammatory and metabolic disorder drugs.
• Cell Signaling Studies: Employed in vitro and in vivo to investigate the role of specific HETE isomers in cellular signaling, inflammation, and immune response pathways.
• Diagnostic Assay Development: Utilized in the development and calibration of immunoassays and LC-MS/MS methods for the quantification of eicosanoids in biological samples.
• Academic Research: A vital tool for universities and research institutions studying arachidonic acid metabolism and its physiological implications.

Basic Information

Product Name	8(S)-Hete
CAS No.	98462-03-4
Molecular Formula	C₂₀H₃₂O₃
Molecular Weight	320.47 g/mol
Synonyms	8(S)-Hydroxyeicosatetraenoic acid; 8(S)-HETE; (8S)-Hydroxy-5Z,9E,11Z,14Z-eicosatetraenoic acid; 8S-HETE; 8(S)-Hydroxy-5,9,11,14-eicosatetraenoic acid; 8S-Hydroxy-5Z,9E,11Z,14Z-eicosatetraenoic Acid
EINECS	Contact for details

Quality Control

Our 8(S)-Hete is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is characterized using advanced analytical techniques including HPLC, GC-MS, and NMR to confirm identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. Keep the container in a dry, well-ventilated area.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Assay	≥ 98%
Stereochemical Purity	≥ 99% (8S-isomer)
Solubility	Soluble in ethanol, DMSO, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.