Description

(1S,2S)-2-((R)-1-Phenylethylamino)Cyclohexanol CAS NO 98361-56-9 is a high-purity chiral amino alcohol derivative, serving as a critical building block in asymmetric synthesis. Its defined stereochemistry makes it an invaluable chiral auxiliary, ligand, or resolving agent for producing enantiomerically pure pharmaceuticals and fine chemicals. This compound is essential for research and production in pharmaceutical development, agrochemical synthesis, and advanced material science, where precise stereocontrol is paramount.

Application

• As a chiral ligand or catalyst in asymmetric hydrogenation and carbon-carbon bond-forming reactions.
• Utilized as a key chiral intermediate in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system and cardiovascular drugs.
• Employed as a resolving agent for the separation of racemic mixtures of carboxylic acids and other chiral compounds.
• Acts as a building block for the preparation of novel chiral ionic liquids and phase-transfer catalysts.
• Used in academic and industrial R&D for method development in stereoselective synthesis.
• Potential application in the synthesis of chiral ligands for metal-organic frameworks (MOFs) and other advanced materials.

Basic Information

Product Name	(1S,2S)-2-((R)-1-Phenylethylamino)Cyclohexanol
CAS No.	98361-56-9
Molecular Formula	C14H21NO
Molecular Weight	219.33 g/mol
Synonyms	(1S,2S)-2-[(1R)-1-Phenylethylamino]cyclohexanol; (1S,2S)-2-[(R)-1-Phenylethylamino]cyclohexan-1-ol; (1S,2S)-(-)-2-[(R)-(+)-1-Phenylethylamino]cyclohexanol; (1S,2S)-2-((R)-α-Methylbenzylamino)cyclohexanol; cis-(1S,2S)-2-((R)-1-Phenylethylamino)cyclohexanol; Chiral Cyclohexanol Derivative; (1S,2S)-N-[(1R)-1-Phenylethyl]cyclohexane-1,2-diamine derivative
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Quality Control

Our (1S,2S)-2-((R)-1-Phenylethylamino)Cyclohexanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) providing specifications for identity, assay, enantiomeric excess, and impurities is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.