Description

17α-Hydroxy-17-[(Z)-2-(125I)-Iodovinyl]Estr-4-En-3-One CAS NO 98256-65-6 is a specialized, radiolabeled steroid derivative designed for advanced research and diagnostic applications. This compound is critical for studies requiring high-precision molecular tracking and receptor binding assays due to its iodine-125 isotope. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and diagnostic developers working in endocrinology and nuclear medicine. The product is supplied to meet the stringent purity and stability requirements essential for sensitive experimental protocols.

Application

• Tracer in Receptor Binding Assays: Used to study the binding affinity and kinetics of steroid hormones to their respective receptors.
• Metabolic Pathway Research: Serves as a radiolabeled probe to trace and quantify metabolic pathways of steroid compounds in vitro and in vivo.
• Diagnostic Agent Development: A key intermediate in the research and development of novel radiopharmaceuticals for diagnostic imaging.
• Biochemical Research: Employed in competitive protein binding assays and other biochemical techniques to understand hormone action.
• Quality Control for Radiopharmaceuticals: Acts as a reference standard in the quality control and validation processes for related therapeutic or diagnostic agents.
• Academic & Pharmaceutical R&D: Essential tool for fundamental research in steroid chemistry, endocrinology, and the development of new therapeutic agents targeting hormone pathways.

Basic Information

Product Name	17α-Hydroxy-17-[(Z)-2-(125I)-Iodovinyl]Estr-4-En-3-One
CAS No.	98256-65-6
Molecular Formula	C20H27IO2 *
Molecular Weight	Contact for details
Synonyms	17α-Hydroxy-17-[(Z)-2-(125I)-iodovinyl]estr-4-en-3-one; (125I)-Iodovinyl Estrenolone; 17α-(125I-Iodovinyl)-19-nortestosterone; 17α-Hydroxy-17-[(Z)-2-(125I)-iodovinyl]estra-4-en-3-one; 17α-(125I)Iodovinyl-19-nortestosterone; Radiolabeled Estrenolone Derivative; 17α-Hydroxy-17-(2-(125I)-iodovinyl)estr-4-en-3-one
EINECS	Contact for details

* Formula is for the non-radiolabeled analog; specific activity for the 125I-labeled product is available upon request.

Quality Control

Every batch of 17α-Hydroxy-17-[(Z)-2-(125I)-Iodovinyl]Estr-4-En-3-One is manufactured and controlled under strict quality systems to ensure high radiochemical purity and specific activity. Quality assurance includes rigorous analytical testing via methods such as Radio-HPLC and TLC. A comprehensive Certificate of Analysis (COA) detailing radiochemical purity, specific activity, and solvent composition is provided with each shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at or below -20°C in a dedicated freezer for radioactive materials. The product is light-sensitive and should be handled in accordance with laboratory safety protocols for radioactive compounds. Allow to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to Off-White Solid
Identification (HPLC)	Conforms to Reference Standard
Radiochemical Purity (Radio-HPLC)	≥ 95%
Specific Activity	Contact for details
Solvent (from NMR)	Specified on COA
Single Impurity (Radio-HPLC)	≤ 2.0%
Total Impurities (Radio-HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.