Description

S(-)Raclopride L-Tartrate >97% Selective D2 Dopamine is a high-purity, enantiomerically pure antagonist with high selectivity for dopamine D2 and D3 receptors. This compound is a critical research-grade standard for neuropharmacological studies, enabling precise investigation of dopaminergic pathways and receptor binding kinetics. It is essential for pharmaceutical R&D, academic neuroscience research, and diagnostic development targeting neurological and psychiatric disorders.

Application

• Neuroscience Research: A key tool for in vitro and in vivo studies of dopamine D2/D3 receptor function, localization, and signaling pathways.
• Radiopharmaceutical Precursor: Used in the synthesis of carbon-11 or fluorine-18 labeled radioligands for Positron Emission Tomography (PET) imaging of the brain.
• Pharmacological Screening: Serves as a reference standard in high-throughput screening (HTS) assays to identify and characterize novel antipsychotic or neurological drug candidates.
• Biochemical Assay Development: Employed in receptor binding assays (e.g., competitive inhibition assays) to determine binding affinities (Ki, IC50) of new chemical entities.
• Academic & Clinical Research: Fundamental for studying the role of dopamine in conditions like schizophrenia, Parkinson's disease, addiction, and mood disorders.
• Quality Control & Reference Standard: Used as a certified reference material (CRM) to validate analytical methods and ensure batch-to-batch consistency in related pharmaceutical manufacturing.

Basic Information

Product Name	S(-)Raclopride L-Tartrate >97% Selective D2 Dopamine
CAS No.	98185-20-7
Molecular Formula	C15H21ClN2O2 • C4H6O6
Molecular Weight	457.88 g/mol (for tartrate salt)
Synonyms	(-)-Raclopride L-Tartrate; (S)-Raclopride L-Tartrate; Raclopride (-)-Tartrate; FLA 870 (-)-Tartrate; (S)-3,5-Dichloro-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-hydroxy-6-methoxybenzamide L-Tartrate; (S)-(-)-Raclopride L-Tartrate; S(-)-Raclopride L-Tartrate Salt; Benzamide, 3,5-dichloro-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-hydroxy-6-methoxy-, (2S,3S)-2,3-dihydroxybutanedioate (1:1)
EINECS	Contact for details

Quality Control

Our S(-)Raclopride L-Tartrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure the specified >97% chemical and enantiomeric purity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	>97.0% (anhydrous basis)
Chiral Purity (HPLC)	>97.0% (S-enantiomer)
Water Content (KF)	< 2.0%
Residue on Ignition	< 0.5%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.