Description

6,7-Difluoroisatoic Anhydride is a high-purity fluorinated heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its role as a key precursor for the development of complex molecules, particularly in the pharmaceutical sector where the introduction of fluorine atoms is a critical strategy for modulating biological activity and metabolic stability. This compound is essential for researchers and manufacturers in medicinal chemistry, agrochemical development, and materials science who require reliable, high-quality intermediates for their R&D and production processes.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of fluorinated quinolone and fluoroquinolone antibiotic analogs, enhancing drug potency and pharmacokinetic profiles.
• Agrochemical Synthesis: Used in the development of novel, high-performance herbicides and pesticides where the difluoro moiety contributes to improved efficacy and environmental stability.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a precursor for electron-transport or emissive layer materials in advanced display technologies.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for transition metal catalysis, enabling novel synthetic transformations.
• Polymer Modification: Used to incorporate fluorinated isatoic anhydride units into polymer backbones, imparting unique thermal, chemical, or surface properties.
• Chemical Research & Development: A valuable reagent for academic and industrial research exploring new fluorination methodologies and heterocyclic chemistry.

Basic Information

Item	Details
Product Name	6,7-Difluoroisatoic Anhydride
CAS No.	97927-59-8
Molecular Formula	C8H3F2NO3
Molecular Weight	199.11 g/mol
Synonyms	6,7-Difluoro-1H-benzo[d][1,3]oxazine-2,4-dione; 6,7-Difluoro-2H-3,1-benzoxazine-2,4(1H)-dione; 6,7-Difluoro-1H-3,1-benzoxazine-2,4-dione; 6,7-Difluoro-2,4-dihydro-1H-3,1-benzoxazine-2,4-dione; 6,7-Difluoroisatoic acid anhydride; 2,4-Dioxo-6,7-difluoro-1,4-dihydro-2H-3,1-benzoxazine; Isatoic Anhydride, 6,7-difluoro-
EINECS	Contact for details

Quality Control

Our 6,7-Difluoroisatoic Anhydride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.