Description

Adenine-2-13C CAS NO 97908-72-0 is a stable isotope-labeled analog of adenine, a fundamental purine base, where the carbon atom at the 2-position is enriched with the 13C isotope. This precise labeling is critical for advanced analytical applications, providing an internal standard for accurate quantification and metabolic pathway tracing using mass spectrometry. It is an essential research tool for scientists and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors who require high-fidelity standards for drug metabolism studies (DMPK), proteomics, and biomarker discovery.

Application

• Internal Standard for Liquid Chromatography-Mass Spectrometry (LC-MS/MS) quantification of adenine and related nucleotides.
• Tracer compound in Metabolic Flux Analysis (MFA) and drug metabolism/pharmacokinetics (DMPK) studies.
• Key precursor for the synthesis of 13C-labeled nucleosides and nucleotides (e.g., adenosine-2-13C).
• Research into purine biosynthesis and salvage pathways in cellular and biochemical research.
• Development and calibration of in vitro diagnostic (IVD) assays and clinical testing methods.
• Use in proteomics and metabolomics research for precise protein and metabolite profiling.

Basic Information

Product Name	Adenine-2-13C
CAS No.	97908-72-0
Molecular Formula	C413CH5N5
Molecular Weight	136.12 g/mol (for 13C-labeled form)
Synonyms	6-Aminopurine-2-13C; 1H-Purin-6-amine-2-13C; Vitamin B4-2-13C; 13C Labeled Adenine; [2-13C]Adenine; Adenine (2-13C); Stable Isotope Labeled Adenine
EINECS	Contact for details

Quality Control

Every batch of Adenine-2-13C is manufactured and analyzed under strict quality protocols to ensure exceptional isotopic and chemical purity, critical for sensitive analytical applications. We provide comprehensive Certificates of Analysis (COA) that detail isotopic enrichment (typically ≥99 atom % 13C), chemical purity (by HPLC), and identity confirmation. Our quality system supports compliance with cGMP standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Enrichment	≥99 atom % 13C
Chemical Purity	≥98.0% (by HPLC)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.