Description

6-Aminopurine-15N2, also known as Vitamin B4, is a stable isotope-labeled analog of adenine, a fundamental building block of nucleic acids and a key metabolite. This labeled compound is essential for advanced research requiring precise metabolic tracing and quantification in biological systems. It is primarily utilized by research institutions, pharmaceutical developers, and diagnostic companies engaged in metabolomics, pharmacokinetic studies, and the development of labeled internal standards for mass spectrometry.

Application

• Metabolic Pathway Tracing: Used as a 15N-labeled tracer in biochemical and pharmacological research to study purine metabolism, nucleotide synthesis, and cellular energy cycles.
• Mass Spectrometry Internal Standard: Serves as a critical isotopic internal standard for the accurate quantification of adenine and its derivatives in complex biological matrices via LC-MS/MS and GC-MS.
• Pharmaceutical Research & Development: Employed in drug metabolism and pharmacokinetics (DMPK) studies to track the fate of drug candidates that are purine analogs or interact with purinergic pathways.
• Diagnostic Assay Development: Integral to developing high-precision clinical diagnostic tests and kits that measure purine-related biomarkers.
• Nutritional and Biochemical Research: Facilitates studies on the role of Vitamin B4 (adenine) in cellular function, nutrition, and related deficiency states.

Basic Information

Product Name	6-Aminopurine-15N2 (Vitamin B4)
CAS No.	97908-71-9
Molecular Formula	C5H515N5
Molecular Weight	137.09 g/mol (for 15N2 labeled form)
Synonyms	Adenine-15N2; 1H-Purin-6-amine-15N2; Vitamin B4-15N2; 6-Aminopurine-15N2; 9H-Purin-6-amine-15N2; [15N2]-Adenine
EINECS	Contact for details

Quality Control

Our 6-Aminopurine-15N2 is manufactured under strict quality systems to ensure high isotopic and chemical purity, critical for research integrity. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (Atom % 15N), chemical purity by HPLC, and identity confirmation. We support compliance with relevant research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (Atom % 15N)	≥ 98%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.