Description

(S)-(+)-o-Anisylmethylphenylphosphine Borane is a high-purity, chiral phosphine-borane complex used as a versatile ligand and chiral auxiliary in asymmetric synthesis. Its value lies in providing exceptional stereocontrol in transition metal-catalyzed reactions, enabling the production of enantiomerically pure intermediates critical for advanced manufacturing. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-performance chiral building blocks for developing new active ingredients and materials.

Application

• Asymmetric Catalysis: As a chiral ligand for transition metals like rhodium, iridium, and palladium in hydrogenation, hydroformylation, and cross-coupling reactions.
• Pharmaceutical Intermediate Synthesis: For the stereoselective construction of chiral centers in active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Development: In the synthesis of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: For manufacturing specialty chemicals, flavors, and fragrances where specific chirality is required for function.
• Academic & Industrial R&D: As a key reagent in methodological development for new asymmetric transformations.
• Chiral Auxiliary: Utilized in stoichiometric asymmetric synthesis to induce chirality, which can later be removed.

Basic Information

Product Name	(S)-(+)-o-Anisylmethylphenylphosphine Borane
CAS No.	97858-63-4
Molecular Formula	C15H20BOP
Molecular Weight	258.11 g/mol
Synonyms	(S)-(-)-o-Anisylmethylphenylphosphine-Borane Complex; (S)-o-(Methoxyphenyl)methylphenylphosphine Borane; (S)-(-)-2-Methoxyphenylmethylphenylphosphine Borane; (S)-Methyl(o-methoxyphenyl)phenylphosphine Borane; (S)-(+)-MOP-Borane; (S)-MOP-BH3; (S)-o-Anisylmethylphenylphosphine-BH3; (S)-2-Methoxybenzylphenylphosphine Borane
EINECS	Contact for details

Quality Control

Our (S)-(+)-o-Anisylmethylphenylphosphine Borane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC, NMR, and elemental analysis. A Certificate of Analysis (COA) detailing purity, enantiomeric excess, and other critical parameters is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.