Description

Batrachotoxinin-A n-Methylanthranilate is a highly potent and specific alkaloid derivative, serving as a critical reference standard and research tool in neuropharmacology. Its primary value lies in its selective and high-affinity interaction with voltage-gated sodium channels, making it indispensable for mechanistic studies. This compound is essential for researchers and institutions in the fields of toxicology, neuroscience, and pharmaceutical development, particularly for investigating channel function, developing antidotes, and studying natural product bioactivity.

Application

• Neuroscience Research: As a potent and selective ligand for studying the structure and function of voltage-gated sodium channels in neuronal signaling.
• Toxicology & Pharmacology: Used as a reference standard for the detection, quantification, and mechanistic study of batrachotoxin and related alkaloids.
• Drug Discovery: A vital tool for screening and evaluating potential neuroprotective agents or sodium channel blockers in high-throughput assays.
• Academic & Institutional Research: Fundamental for biochemical and electrophysiological studies in university and government laboratories.
• Biochemical Assay Development: Employed in the development and validation of sensitive analytical methods (e.g., HPLC-MS, ELISA) for toxin analysis.
• Natural Product Chemistry: Serves as a key compound for comparative studies on the structure-activity relationships of amphibian-derived toxins.

Basic Information

Product Name	Batrachotoxinin-A n-Methylanthranilate
CAS No.	97779-14-1
Molecular Formula	C32H42N2O5
Molecular Weight	534.70 g/mol
Synonyms	Batrachotoxinin A 20α-N-Methylanthranilate; Batrachotoxinin A o-Methylanthranilate; 3β,9α-Epoxy-14β,18β-(2-methyl-2,5-epoxy-4-phenyl-2,5-dihydro-1H-pyrrol-3-yl)-14,15-seco-5β-pregnane-14,15,16-triol 16-Acetate 20α-(N-Methylanthranilate); BTX-A n-Methylanthranilate; Batrachotoxinin A Anthranilate Derivative
EINECS	Contact for details

Quality Control

Our Batrachotoxinin-A n-Methylanthranilate is produced and handled under strict quality protocols to ensure the highest standards of purity and identity required for research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We adhere to ISO 9001 quality management principles, and our analytical methods are validated to meet the rigorous demands of scientific research. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. This compound is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider storing desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 95.0% (Area Percent)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.