Description

Hydroxy-β-Sanshool is a bioactive alkylamide compound, a key constituent responsible for the tingling and numbing sensation associated with Szechuan peppers. This compound matters for its unique pharmacological profile, offering a distinct sensory experience and potential for research into novel topical agents and flavor modulators. It is needed by researchers and product developers in the pharmaceutical, nutraceutical, and food & beverage industries seeking natural bioactive ingredients for sensory modulation and therapeutic applications.

Application

• Pharmaceutical Research: Investigated for its TRPV1 and TRPA1 channel agonist activity in studies related to topical analgesics, anti-itch formulations, and novel pain management pathways.
• Nutraceutical Formulations: Used as a key bioactive component in dietary supplements targeting metabolic health and natural wellness, leveraging its bioactivity.
• Food & Beverage Industry: Serves as a natural flavoring and sensory agent to create the characteristic "tingling" or numbing sensation in gourmet foods, seasonings, and innovative beverages.
• Cosmetic & Personal Care: Incorporated into skincare products for its potential stimulating and reviving effects on the skin, such as in lip plumpers or facial treatments.
• Neuroscience Research: A valuable tool for studying somatosensory transduction, particularly the mechanisms of chemesthesis (chemical sensitivity) in the skin and mucous membranes.
• Agrochemical Research: Explored for its natural bioactive properties in the development of novel, plant-derived pest management solutions.

Basic Information

Product Name	Hydroxy-β-Sanshool
CAS No.	97465-69-5
Molecular Formula	C16H25NO2
Molecular Weight	263.38 g/mol
Synonyms	Hydroxy-β-sanshool; (2E,6E,8E,10E)-N-(2-Hydroxy-2-methylpropyl)dodeca-2,6,8,10-tetraenamide; β-Hydroxysanshool; Hydroxysanshool; Sanshool isomer; Zanthoxylum alkylamide; Szechuan pepper tingling agent
EINECS	Contact for details

Quality Control

Our Hydroxy-β-Sanshool is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing specific results for purity, related substances, and other critical parameters is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation and ensure long-term stability. The container should be kept in a cool, dry, and well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance	Pale yellow to yellow viscous liquid or solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solubility	Soluble in ethanol, DMSO; slightly soluble in oils

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.