Description

Isohumulone is a key isomer of the α-acid humulone, primarily derived from hops (Humulus lupulus). This compound is of significant commercial interest due to its role as a precursor to the bittering agents formed during the beer brewing process. It is essential for manufacturers in the brewing industry, flavor and fragrance sectors, and research institutions focused on hop chemistry and product development. Isohumulone CAS NO 10306-63-5 is a critical component for achieving the characteristic bitter flavor profile in beer.

Application

• Beer Bittering Agent: Primary application as the precursor to iso-alpha acids, which provide the characteristic bitter taste in beer during wort boiling.
• Flavoring Agent: Used in the development and standardization of bitter flavors for alcoholic and non-alcoholic beverages.
• Food Additive: Employed as a natural bittering agent in various food products beyond beverages.
• Pharmaceutical & Nutraceutical Research: Studied for its potential bioactive properties, including antimicrobial and anti-inflammatory effects.
• Hop Extract Production: A standard component in refined hop extracts and products used for consistent brewing bittering value.
• Analytical Reference Standard: Serves as a high-purity chemical standard for quality control and research in brewing science and food chemistry.

Basic Information

Product Name	Isohumulone
CAS No.	10306-63-5
Molecular Formula	C21H30O5
Molecular Weight	362.46 g/mol
Synonyms	Isohumulone; (3R,4S)-3,4-Dihydroxy-5-methoxy-2-(3-methylbut-2-en-1-yl)-4-(3-methylbutanoyl)cyclopent-2-en-1-one; 4,5-Dihydroxy-3-(3-methyl-2-butenyl)-2-(3-methyl-1-oxobutyl)-4-cyclopentene-1,3-dione; trans-Isohumulone; Iso-alpha acid; Iso-α-acid; Isohumulon; Hop bitter acid isomer
EINECS	233-675-7

Quality Control

Our Isohumulone is produced and tested to meet high-purity standards suitable for food, flavor, and research applications. Each batch is analyzed to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting key parameters such as assay, related substances, and optical rotation are available upon request. We adhere to GMP principles in our manufacturing processes to ensure reliable quality for our global B2B customers.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). For long-term storage, consider packaging under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	Yellow to amber powder or resin
Identification (IR)	Conforms to structure
Assay (HPLC)	≥95.0%
Related Substances (HPLC)	Total impurities ≤5.0%
Specific Rotation	Contact for details
Loss on Drying	≤2.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.