Description

Homodihydrocapsaicin is a capsaicinoid analog, a key compound in the study of TRPV1 receptor activity and sensory modulation. This high-purity standard is essential for research and development in pharmacology and neuroscience, offering a critical tool for understanding pain pathways and developing novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of reference standards and analytical reagents.

Application

• Pharmaceutical Research & Development: As a reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel analgesics and topical pain relief formulations.
• Neuroscience & Pharmacology Studies: For in-vitro and in-vivo research targeting the TRPV1 (vanilloid) receptor to study pain sensation, neurogenic inflammation, and thermoregulation.
• Analytical Reference Standard: Used in high-performance liquid chromatography (HPLC), gas chromatography (GC), and mass spectrometry (MS) for the identification, purity assessment, and quantification of capsaicinoids in complex matrices.
• Food & Flavor Science: Employed in the study and calibration of pungency (Scoville Heat Units) in chili peppers and food products, though at lower concentrations than capsaicin.
• Cosmetic & Personal Care R&D: Investigated for potential use in topical formulations aimed at stimulating circulation or providing a warming sensation, subject to regional regulatory approval.
• Agrochemical Research: Studied for its potential as a natural, bioactive compound in pest management strategies.

Basic Information

Product Name	Homodihydrocapsaicin
CAS No.	20279-06-5
Molecular Formula	C18H29NO3
Molecular Weight	307.43 g/mol
Synonyms	Homodihydrocapsaicin; Dihydrohomocapsaicin; N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methylnonanamide; Nonivamide derivative; Capsaicin analog; (E)-N-(4-Hydroxy-3-methoxybenzyl)-8-methylnon-6-enamide (isomeric); Vanillylamide of 8-methylnonanoic acid
EINECS	Contact for details

Quality Control

Our Homodihydrocapsaicin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR). Certificates of Analysis (COA) detailing batch-specific results are provided to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Melting Point	62 - 66 °C
Loss on Drying	≤ 1.0 %
Residue on Ignition	≤ 0.1 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.