Description

trans-Rho-1-Isohumulone CAS NO 16892-01-6 is a specific, purified isomer of isohumulone, a key class of bittering compounds derived from hops. This compound is of significant commercial interest due to its role in defining the precise flavor profile, bitterness, and stability of beer and other hop-flavored beverages. It is an essential analytical standard and a critical component for brewers, flavor houses, and food scientists focused on quality control, product consistency, and innovative flavor development.

Application

• Beer Bitterness Standardization: Used as a high-purity reference standard to accurately measure and calibrate the International Bitterness Units (IBU) in beer.
• Flavor and Sensory Research: Essential for studying the specific sensory impact of individual hop-derived iso-alpha acids on beer flavor, aroma, and mouthfeel.
• Brewing Process Optimization: Employed in research to understand isomerization kinetics and stability of bittering compounds during the brewing and storage processes.
• Quality Control (QC) and Assurance: Serves as a critical component in HPLC and other analytical methods for quantifying iso-alpha acid content in hops, hop products, and finished beer.
• Food and Beverage Flavoring: Potential use as a defined bittering agent in the development of non-alcoholic beverages, specialty foods, and nutraceuticals seeking a consistent hop character.
• Academic and Industrial Research: A vital reagent for chemical, biochemical, and pharmacological studies related to hop constituents.

Basic Information

Product Name	trans-Rho-1-Isohumulone
CAS No.	16892-01-6
Molecular Formula	C21H30O5
Molecular Weight	362.46 g/mol
Synonyms	(E)-Rho-1-Isohumulone; trans-ρ-1-Isohumulone; (E)-4,6-Dihydroxy-3-(3-methylbut-2-en-1-yl)-2-(3-methyl-1-oxobutyl)-6-(4-methylpent-3-en-1-yl)cyclohexa-2,4-dien-1-one; 1-Isohumulone, trans-Rho- isomer; Isohumulone B (related); Iso-alpha acid standard; Hop bitter acid isomer
EINECS	240-948-9

Quality Control

Our trans-Rho-1-Isohumulone is produced and handled under strict quality protocols to ensure the highest purity and consistency, suitable for analytical and research applications. Each batch is thoroughly characterized using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and related substances is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) to minimize oxidation. Keep the container in a cool, dry, and well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to Amber Powder or Solid
Identification (HPLC)	Conforms to Reference Standard
Identification (IR)	Conforms to Reference Spectrum
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solubility	Soluble in Methanol, Ethanol; Slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.