Description

Hydroxy-ε-Sanshool is a bioactive alkylamide compound, a key sensory agent responsible for the characteristic tingling and numbing sensation. This compound is of significant commercial interest due to its unique physiological effects, which are leveraged in various consumer and pharmaceutical products. It is primarily sought by manufacturers in the flavor and fragrance, nutraceutical, and topical analgesic industries for its ability to modulate sensory perception.

Application

• As a key sensory additive in flavor formulations to create tingling, cooling, or numbing sensations in foods, beverages, and confectionery.
• As an active ingredient in topical analgesic and cosmetic formulations for its counter-irritant and soothing properties.
• In nutraceutical and dietary supplement products targeting oral health or sensory enhancement.
• As a reference standard for analytical testing and quality control in laboratories.
• For pharmacological research into TRP channel modulation and sensory neuron activity.
• In personal care products such as mouthwashes, toothpastes, and lip balms for a unique sensory profile.

Basic Information

Product Name	Hydroxy-ε-Sanshool
CAS No.	252193-26-3
Molecular Formula	C₁₆H₂₅NO₂
Molecular Weight	263.38 g/mol
Synonyms	(2E,6E,8E,10E)-N-(2-Hydroxy-2-methylpropyl)dodeca-2,6,8,10-tetraenamide; Hydroxy-ε-sanshool; Hydroxy-ε-sanshool; Sanshool derivative; Alkylamide; Spilanthol analog
EINECS	Contact for details

Quality Control

Our Hydroxy-ε-Sanshool is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets stringent specifications. Certificates of Analysis (COA) detailing all test results are provided with every shipment to guarantee traceability and consistency for your formulations and research.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This product is light-sensitive and easily oxidized; minimize exposure to air, light, and moisture during handling.

Specification

Item	Specification
Appearance	Pale yellow to yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solvent Residue (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.