Description

cis-Isohumulone is a key isomer of isohumulone, a principal component of hop-derived bitter acids in beer. This compound is critical for defining the precise bitterness profile, flavor stability, and foam quality of finished beer. It is an essential analytical standard and process control reagent for breweries, flavor houses, and suppliers in the global beverage industry seeking to optimize and standardize their products.

Application

• Beer Bitterness Standardization: Used as a high-purity reference standard for the quantification of iso-alpha acids in beer and wort via HPLC, ensuring consistent bittering levels.
• Flavor and Stability Research: Employed in studies to understand the impact of specific iso-alpha acid isomers on flavor development, shelf-life, and light-stability (anti-skunking) in beer.
• Quality Control in Brewing: Serves as a critical calibrant for in-process quality control laboratories to monitor hopping efficiency and bitter acid isomerization during kettle boiling.
• Hop Product Analysis: Essential for the analysis and certification of commercial hop extracts, isomerized pellets, and advanced hop products to verify isomer content and purity.
• Sensory Science: Used to prepare defined solutions for sensory panel training and to investigate the individual taste thresholds and characteristics of different bitter acid isomers.

Basic Information

Product Name	cis-Isohumulone
CAS No.	35928-10-0
Molecular Formula	C21H30O5
Molecular Weight	362.46 g/mol
Synonyms	(3R,5R)-3,5,6-Trihydroxy-4-(3-methylbutanoyl)-2-(3-methylbutyl)-4,6-cyclohexadien-1-one; cis-Iso-α-acid; (Z)-Isohumulone; Isohumulone A; trans-Isohumulone Isomer; Beer Bitter Acid Isomer; Hop Bitter Acid Standard
EINECS	Contact for details

Quality Control

Our cis-Isohumulone is produced and handled under strict quality management protocols. Each batch is analyzed to ensure high chemical purity and identity confirmation, making it suitable for use as an analytical reference standard. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and chromatographic profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) to minimize oxidation. Keep the container in a cool, dry, and well-ventilated area separate from strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to Amber Powder or Solid
Identification (HPLC)	Conforms to Reference Standard
Identification (IR)	Conforms to Structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total related isomers ≤ 5.0%
Water Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.