Description

L-Milnacipran Hydrochloride is a high-purity pharmaceutical intermediate and active pharmaceutical ingredient (API). This compound is the active enantiomer of the antidepressant Milnacipran, offering significant value for the development of targeted therapeutic agents. It is primarily required by pharmaceutical manufacturers and advanced research institutions for the synthesis of novel antidepressant medications and for pharmacological studies.

Application

• Pharmaceutical API Synthesis: Primary use as the active ingredient in the manufacture of enantiomerically pure antidepressant drugs.
• Research & Development: Critical material for preclinical and clinical studies investigating serotonin-norepinephrine reuptake inhibitors (SNRIs).
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory testing in pharmaceutical labs.
• Process Development: Used in the optimization and scale-up of chiral synthesis routes within process chemistry.
• Academic Research: Employed in universities and research institutes for neuropharmacology and medicinal chemistry projects.

Basic Information

Product Name	L-Milnacipran Hydrochloride
CAS No.	96847-54-0
Molecular Formula	C15H23ClN2O
Molecular Weight	282.81 g/mol
Synonyms	(1S,2R)-Milnacipran Hydrochloride; Levomilnacipran Hydrochloride; F2695 Hydrochloride; (1S,2R)-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide Hydrochloride; (1S,2R)-2-[(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide Hydrochloride; L-Milnacipran HCl; Fetzima™ (brand name API)
EINECS	Contact for details

Quality Control

Our L-Milnacipran Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets stringent pharmaceutical-grade specifications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.