Description

Ethyl 3,5-Bis(Trifluoromethyl)Benzoate is a high-value fluorinated aromatic ester, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring two powerful electron-withdrawing trifluoromethyl groups, makes it indispensable for introducing specific steric and electronic properties into target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for creating novel active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the trifluoromethyl groups improve lipophilicity and biological activity.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis, enabling challenging cross-coupling reactions.
• Material Science Research: Acts as a monomer or modifier in the synthesis of fluorinated polymers and advanced organic electronic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring fluorinated aromatic cores.

Basic Information

Product Name	Ethyl 3,5-Bis(Trifluoromethyl)Benzoate
CAS No.	96617-71-9
Molecular Formula	C11H8F6O2
Molecular Weight	286.17 g/mol
Synonyms	Ethyl 3,5-Bis(trifluoromethyl)benzoate; Benzoic acid, 3,5-bis(trifluoromethyl)-, ethyl ester; 3,5-Bis(trifluoromethyl)benzoic Acid Ethyl Ester; Ethyl α,α,α,α',α',α'-Hexafluoro-3,5-xylene-2-carboxylate; 96617-71-9; Ethyl 3,5-di(trifluoromethyl)benzoate
EINECS	Contact for details

Quality Control

Every batch of Ethyl 3,5-Bis(Trifluoromethyl)Benzoate is produced and tested under a strict quality management system. We guarantee high chemical purity and consistency, supported by comprehensive analytical documentation. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to ensure it meets your precise research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids, strong bases, and oxidizing agents. Recommended storage temperature is between 2°C and 25°C. The container should be kept tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.