Description

(S)-(+)-Epiboromohydrin is a high-value chiral building block and versatile electrophilic reagent used in advanced organic synthesis. Its importance lies in its ability to introduce both an epoxide ring and a boronate ester functionality, enabling stereoselective transformations and the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key chiral precursor for the synthesis of active pharmaceutical ingredients (APIs), particularly in routes requiring stereocontrolled epoxide ring-opening or Suzuki-Miyaura cross-coupling reactions.
• Agrochemical Synthesis: Used in the production of chiral herbicides, fungicides, and plant growth regulators where specific stereochemistry is critical for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing novel chiral ligands and organocatalysts used in asymmetric catalysis.
• Polymer & Material Science: Employed in the creation of functionalized polymers, dendrimers, and advanced materials with tailored properties.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules due to its reactive epoxide and handle for further functionalization via the boronate.
• Academic & Process R&D: A critical reagent for methodological development in organic chemistry and scale-up process optimization.

Basic Information

Product Name	(S)-(+)-Epiboromohydrin
CAS No.	96479-96-8
Molecular Formula	C3H6BBrO
Molecular Weight	148.80 g/mol
Synonyms	(S)-(-)-1-Bromo-3-borirane; (S)-(+)-1-Bromo-3-borolane; (S)-1-Bromo-3-borolen; (S)-Epibromoborane; (S)-Epoxypropylboronic acid, cyclic ester; (S)-Glycidylboronate; (S)-Oxiranylmethylboronic acid, cyclic ester; B-Bromo-1,2-epoxypropylboronate
EINECS	Contact for details

Quality Control

Our (S)-(+)-Epiboromohydrin is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is characterized by comprehensive analytical techniques including chiral HPLC, NMR, and GC to confirm identity, enantiomeric excess, and purity. Certificates of Analysis (COA) with full specification data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C under an inert atmosphere (e.g., argon or nitrogen) due to its moisture-sensitive and light-sensitive nature. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (Karl Fischer)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.