Description

1,2-Cyclopropanedicarboxylic Acid Bis [(1R, 2S, 5R)]-5-Methyl-2-(1-Methylethyl) is a high-purity, chiral chemical intermediate of significant importance in advanced organic synthesis. Its defined stereochemistry makes it a valuable building block for creating complex molecules with specific three-dimensional structures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and production of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where specific stereochemistry is crucial for biological activity and environmental safety.
• Catalyst and Ligand Preparation: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis to control reaction stereoselectivity.
• Material Science Research: Employed in academic and industrial R&D for creating novel polymers or functional materials with tailored properties derived from its rigid cyclopropane structure.
• Fine Chemical Production: A critical component in multi-step synthetic routes for other high-value specialty chemicals and flavors & fragrances.

Basic Information

Product Name	1,2-Cyclopropanedicarboxylic Acid Bis [(1R, 2S, 5R)]-5-Methyl-2-(1-Methylethyl)
CAS No.	96149-00-7
Molecular Formula	C17H28O4
Molecular Weight	296.40 g/mol
Synonyms	(1R,2S,5R)-Menthyl (1R,2S)-cyclopropane-1,2-dicarboxylate; (-)-Menthyl (1R,2S)-1,2-cyclopropanedicarboxylate; L-Menthyl (1R,2S)-Cyclopropane-1,2-dicarboxylate; (1R,2S)-Cyclopropane-1,2-dicarboxylic Acid Bis-[(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl] Ester; (-)-Menthyl (1R,2S)-Cyclopropanedicarboxylate; Cyclopropane-1,2-dicarboxylic acid bis[(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl] ester
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high enantiomeric purity. Quality is verified through advanced analytical techniques including HPLC, chiral GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with each shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to prevent moisture absorption and maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral GC/HPLC)	≥ 99.0% e.e.
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.