Description

4α-[[2-(Acetylamino)-2-Deoxy-4-o-Sodiosulfo-β-D-Glucopyranosyl]Oxy]-5β-(Hydroxymethyl)-L-Proline is a specialized, high-purity chemical building block of significant interest in advanced pharmaceutical synthesis and biochemical research. Its complex molecular structure, featuring a modified glucopyranosyl moiety linked to a proline derivative, makes it a critical intermediate for developing novel therapeutic agents and research tools. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of glycosidase inhibitors, glycopeptide antibiotics, and other bioactive molecules targeting carbohydrate-processing pathways.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel glycopeptide-based drugs and enzyme inhibitors.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly for glycosidases and glycosyltransferases.
• Glycoconjugate Synthesis: Serves as a sophisticated building block for the chemical and enzymatic synthesis of complex oligosaccharides and glycoproteins.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of carbohydrate-based therapeutics.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	4α-[[2-(Acetylamino)-2-Deoxy-4-o-Sodiosulfo-β-D-Glucopyranosyl]Oxy]-5β-(Hydroxymethyl)-L-Proline
CAS No.	95975-85-2
Molecular Formula	C18H29N2NaO12S
Molecular Weight	520.49 g/mol
Synonyms	L-Proline, 4-[[2-(acetylamino)-2-deoxy-4-O-sodio-β-D-glucopyranosyl]oxy]-5-(hydroxymethyl)-; 4-[[2-(Acetylamino)-2-Deoxy-4-O-sodio-β-D-glucopyranosyl]oxy]-5-(hydroxymethyl)-L-proline; 4-O-(2-Acetamido-2-deoxy-4-O-sodio-β-D-glucopyranosyl)-5-(hydroxymethyl)-L-proline; N-Acetylglucosamine-L-proline derivative, sodium salt; 95975-85-2; 4α-[[2-(Acetylamino)-2-Deoxy-4-o-Sodiosulfo-β-D-Glucopyranosyl]oxy]-5β-(Hydroxymethyl)-L-Proline
EINECS	Contact for details

Quality Control

Every batch of 4α-[[2-(Acetylamino)-2-Deoxy-4-o-Sodiosulfo-β-D-Glucopyranosyl]Oxy]-5β-(Hydroxymethyl)-L-Proline is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay (HPLC), chiral purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Chiral Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.