Description

(R)-(+)-Hepialone is a high-purity chiral compound of significant interest in advanced organic synthesis and pharmaceutical research. Its defined stereochemistry makes it a valuable building block for the development of enantiomerically pure active pharmaceutical ingredients (APIs) and fine chemicals. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop or produce optically active compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly where specific enantiomeric activity is required.
• Asymmetric Synthesis: Used as a starting material or reagent in catalytic asymmetric reactions to construct complex molecular architectures with high stereoselectivity.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals, including flavors, fragrances, and advanced materials.
• Agrochemical Research: Serves as a precursor in the development of new chiral pesticides and herbicides with potentially improved efficacy and environmental profiles.
• Academic & Industrial R&D: A critical tool for chemists in universities and corporate labs studying reaction mechanisms, catalysis, and stereochemistry.
• Reference Standard: Can be utilized as an analytical standard for method development and quality control in chiral separation techniques like HPLC and SFC.

Basic Information

Product Name	(R)-(+)-Hepialone
CAS No.	95833-18-4
Molecular Formula	C11H14O3
Molecular Weight	194.23 g/mol
Synonyms	(R)-Hepialone; (+)-Hepialone; (R)-(+)-4,5-Dimethyl-3a,4,5,6-tetrahydro-3H-isobenzofuran-1-one; 3a,4,5,6-Tetrahydro-4,5-dimethyl-3H-2-benzofuran-1-one, (3aR,4S,5R)-rel-; Hepialone, (R)-(+)-
EINECS	Contact for details

Quality Control

Our (R)-(+)-Hepialone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles, typically determined by advanced chromatographic methods (HPLC, GC) and spectroscopic techniques (NMR, IR). We support compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product should be kept under an inert atmosphere if long-term storage is required to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Purity (Chiral HPLC)	≥ 99.0% ee
Specific Rotation	Contact for details
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.