Description

(S)-3-Hydroxyglutarate Ethyl is a high-purity chiral building block and synthetic intermediate of significant value in advanced organic synthesis. This compound matters for its role in the stereoselective construction of complex molecules, particularly in pharmaceutical research and development. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for applications requiring precise stereochemical control.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of active pharmaceutical ingredients (APIs), especially those targeting metabolic pathways or requiring specific stereochemistry.
• Biochemical Research: Used as a precursor or standard in metabolic studies, enzyme inhibition assays, and proteomics research.
• Asymmetric Synthesis: Serves as a starting material or chiral auxiliary in catalytic asymmetric reactions to produce enantiomerically pure compounds.
• Agrochemical Development: Intermediate in the synthesis of novel, stereospecific herbicides, fungicides, or plant growth regulators.
• Fine Chemical Production: Building block for specialty chemicals, flavors, fragrances, and advanced materials where optical purity is critical.
• Academic & Industrial R&D: Utilized in methodological development and discovery chemistry within university and corporate laboratories.

Basic Information

Product Name	(S)-3-Hydroxyglutarate Ethyl
CAS No.	95310-88-6
Molecular Formula	C7H12O5
Molecular Weight	176.17 g/mol
Synonyms	Ethyl (S)-3-Hydroxyglutarate; (S)-Ethyl 3-Hydroxyglutarate; (3S)-3-Hydroxypentanedioic Acid Diethyl Ester; (S)-3-Hydroxy-1,5-pentanedioic Acid Diethyl Ester; (S)-3-Hydroxyglutaric Acid Diethyl Ester; (S)-Diethyl 3-Hydroxyglutarate; (S)-3-HG Ethyl Ester; (S)-3-Hydroxypentanedioic Acid Diethyl Ester
EINECS	Contact for details

Quality Control

Our (S)-3-Hydroxyglutarate Ethyl is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for research and development use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.