Description

Ethyl (R)-(+)-4-Bromo-3-Hydroxybutyrate is a high-value chiral building block and synthetic intermediate of significant importance in asymmetric synthesis. Its defined stereochemistry makes it a critical precursor for the production of optically active pharmaceuticals and fine chemicals. This compound is essential for research and manufacturing chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require enantiomerically pure intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of statin drugs (e.g., cholesterol-lowering agents like Atorvastatin and Rosuvastatin) and other bioactive molecules.
• Asymmetric Synthesis: Used in stereoselective reactions to construct complex molecular architectures with high enantiomeric excess.
• Agrochemical Production: Serves as a precursor for chiral active ingredients in herbicides, fungicides, and pesticides.
• Fine Chemical Synthesis: Employed in the manufacture of specialty chemicals, flavors, fragrances, and liquid crystals.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and process chemistry optimization.
• Bioconjugate Chemistry: Potential use in the synthesis of labeled compounds or probes for biochemical studies.

Basic Information

Product Name	Ethyl (R)-(+)-4-Bromo-3-Hydroxybutyrate
CAS No.	95310-48-8
Molecular Formula	C6H11BrO3
Molecular Weight	211.06 g/mol
Synonyms	(R)-Ethyl 4-Bromo-3-hydroxybutyrate; (R)-(+)-4-Bromo-3-hydroxybutyric Acid Ethyl Ester; Ethyl (R)-4-Bromo-3-hydroxybutanoate; (R)-BHBE; (3R)-4-Bromo-3-hydroxybutyric acid ethyl ester; (R)-Ethyl 4-bromo-3-hydroxybutanoate; Ethyl (R)-4-bromo-3-hydroxybutyrate; (R)-(-)-4-Bromo-3-hydroxybutyric acid ethyl ester (Note: Verify specific rotation sign with supplier)
EINECS	Contact for details

Quality Control

Our Ethyl (R)-(+)-4-Bromo-3-Hydroxybutyrate is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure high chemical and enantiomeric purity, meeting the stringent requirements of pharmaceutical development. Certificates of Analysis (COA) detailing assay, chiral purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.