Description

Cyclopropanamine, 1-Phenyl-, Labeled With Carbon-14, Hydrochloride (9Ci) is a high-purity, isotopically labeled chemical reference standard essential for advanced research and development. This compound is specifically designed for use as a radiolabeled tracer in metabolic, pharmacokinetic, and environmental fate studies, providing critical data for regulatory submissions. It is primarily utilized by pharmaceutical, agrochemical, and contract research organizations (CROs) engaged in drug discovery, safety assessment, and analytical method development.

Application

• Radiolabeled Tracer in ADME Studies: Used to track the absorption, distribution, metabolism, and excretion (ADME) of new chemical entities in preclinical research.
• Metabolic Pathway Elucidation: Enables the identification and quantification of drug metabolites in complex biological matrices.
• Environmental Fate and Residue Analysis: Applied in agrochemical research to study degradation pathways and environmental persistence.
• Quantitative Bioanalysis: Serves as an internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and Liquid Scintillation Counting (LSC) for precise quantification.
• Mechanistic Biochemical Research: Facilitates the study of enzyme mechanisms and receptor-ligand interactions where the cyclopropylamine pharmacophore is involved.
• Reference Material for Method Validation: Used to develop and validate sensitive analytical methods in compliance with GLP and GMP guidelines.

Basic Information

Product Name	Cyclopropanamine, 1-Phenyl-, Labeled With Carbon-14, Hydrochloride (9Ci)
CAS No.	95216-83-4
Molecular Formula	C9H914ClN * (HCl) *Carbon-14 labeled position may vary; contact for details
Molecular Weight	~185.64 g/mol (unlabeled hydrochloride salt) *Exact value depends on specific activity
Synonyms	1-Phenylcyclopropanamine-14C Hydrochloride; 1-Phenylcyclopropylamine-14C HCl; [14C]-1-Phenylcyclopropanamine Hydrochloride; (1-Phenylcyclopropyl)amine-14C Hydrochloride; 1-Aminocyclopropylbenzene-14C Hydrochloride; 1-Phenyl-1-cyclopropanamine-14C Hydrochloride; 9Ci Labeled 1-Phenylcyclopropanamine HCl; NSC 163022-14C (Hydrochloride)
EINECS	Contact for details

Quality Control

Every batch of this radiolabeled compound is manufactured and analyzed under strict quality systems to ensure high chemical, radiochemical, and isomeric purity. Our quality commitment includes comprehensive testing via HPLC, NMR, and mass spectrometry to confirm identity, specific activity, and radiochemical purity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical parameters. Production and handling adhere to relevant radiation safety and quality guidelines to ensure material integrity and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated, appropriately shielded freezer for radioactive materials. This product is hygroscopic (moisture-sensitive); ensure containers are sealed under inert atmosphere if specified. Follow all local and international regulations for the safe storage and handling of radioactive substances.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR / NMR)	Conforms to structure
Assay (HPLC)	≥ 98% (chemical purity)
Radiochemical Purity (HPLC)	≥ 97%
Specific Activity	Customizable (Contact for details)
Solvent (if supplied as solution)	Specified on COA
Radioactive Concentration	Specified on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.