Description

Methyl 4-(1,1,2,2-Tetrafluoroethoxy)Benzoate is a high-purity fluorinated aromatic ester, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in the unique combination of the benzoate ester moiety and the tetrafluoroethoxy group, which imparts enhanced stability, lipophilicity, and specific electronic properties to target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and specialty materials where fluorine incorporation is strategically advantageous.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting CNS disorders, anti-inflammatory agents, and antiviral compounds.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and plant growth regulators, where the fluorinated side chain can improve biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, contributing to improved dielectric anisotropy, thermal stability, and optical performance.
• Polymer & Specialty Chemicals: Employed in the modification of polymers and resins to introduce fluorine, thereby enhancing properties like chemical resistance, weatherability, and surface characteristics.
• Organic Synthesis & Catalysis: Acts as a versatile reagent in cross-coupling reactions and as a substrate for exploring new fluorination methodologies and catalytic processes in academic and industrial R&D.

Basic Information

Product Name	Methyl 4-(1,1,2,2-Tetrafluoroethoxy)Benzoate
CAS No.	93982-47-9
Molecular Formula	C10H8F4O3
Molecular Weight	252.16 g/mol
Synonyms	Benzoic acid, 4-(1,1,2,2-tetrafluoroethoxy)-, methyl ester; Methyl p-(1,1,2,2-tetrafluoroethoxy)benzoate; 4-(1,1,2,2-Tetrafluoroethoxy)benzoic acid methyl ester; Methyl 4-(perfluoroethoxy)benzoate (common name); Methyl 4-(β,β,β',β'-tetrafluoroethoxy)benzoate; 93982-47-9; Methyl 4-(TFE)benzoate
EINECS	Contact for details

Quality Control

Our Methyl 4-(1,1,2,2-Tetrafluoroethoxy)Benzoate is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from strong bases and fluorides.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.