Description

[10,11-Dihydro-5H-Dibenz[B,F]Azepine-5-Propyl]Dimethylammonium Hydrogen Maleate is a high-purity pharmaceutical intermediate and active ingredient salt form. This compound is critical for ensuring the stability, bioavailability, and efficacy of final drug formulations. It is primarily required by pharmaceutical R&D laboratories, API manufacturers, and fine chemical suppliers engaged in the development of advanced therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) for central nervous system (CNS) and neurological disorder treatments.
• Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control testing in regulatory submissions.
• Preclinical & Clinical Research: Serves as a critical material in pharmacological studies, toxicology assessments, and formulation development during drug discovery phases.
• Process Chemistry: Employed in scale-up and optimization of synthetic routes for the production of target drug molecules.
• Academic Research: Utilized in university and institutional laboratories for studying structure-activity relationships (SAR) and novel synthetic methodologies.

Basic Information

Product Name	[10,11-Dihydro-5H-Dibenz[B,F]Azepine-5-Propyl]Dimethylammonium Hydrogen Maleate
CAS No.	93980-91-7
Molecular Formula	C22H28N2O4
Molecular Weight	384.47 g/mol
Synonyms	Dimethyl(3-{5H-dibenzo[b,f]azepin-5-yl}propyl)ammonium hydrogen maleate; 5-(3-Dimethylaminopropyl)-10,11-dihydro-5H-dibenzo[b,f]azepine hydrogen maleate; Desipramine Impurity F Maleate; Desmethylimipramine Maleate; Norimipramine Maleate; NSC 114895; 10,11-Dihydro-5-(3-(dimethylamino)propyl)-5H-dibenzo[b,f]azepine maleate (1:1)
EINECS	Contact for details

Quality Control

Our [10,11-Dihydro-5H-Dibenz[B,F]Azepine-5-Propyl]Dimethylammonium Hydrogen Maleate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by spectroscopic methods (IR, NMR), to ensure it meets stringent pharmaceutical-grade standards. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.