Description

Reboxetine Mesylate is the mesylate salt form of the selective norepinephrine reuptake inhibitor (NRI), reboxetine. This high-purity active pharmaceutical ingredient (API) is critical for ensuring the efficacy and consistency of finished pharmaceutical formulations. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in the development and production of antidepressant medications. The compound is supplied under stringent quality control to meet the exacting standards of the global pharmaceutical industry.

Application

• Primary API in Antidepressant Formulations: Serves as the core active ingredient in the manufacture of antidepressant drugs targeting major depressive disorder.
• Neurological Research Compound: Used in preclinical and clinical research to study norepinephrine pathways and their role in mood disorders and cognition.
• Pharmaceutical Reference Standard: Employed as a high-purity standard in analytical laboratories for quality control, method development, and regulatory testing of drug products.
• Formulation Development: Integral to R&D for developing various dosage forms, including tablets and capsules, ensuring stability and bioavailability.
• Generic Drug Manufacturing: A key component for companies producing bioequivalent generic versions of branded reboxetine-based medications.

Basic Information

Product Name	Reboxetine Mesylate
CAS No.	93851-87-7
Molecular Formula	C19H23NO3 • CH4O3S
Molecular Weight	409.50 g/mol
Synonyms	Reboxetine methanesulfonate; FCE 20124; (RS)-2-[(RS)-α-(2-Ethoxyphenoxy)benzyl]morpholine methanesulfonate; (R*,S*)-2-[(α-(2-Ethoxyphenoxy)benzyl]morpholine methanesulfonate; Reboxetine mesilate; Reboxetine Metilsulfate
EINECS	Contact for details

Quality Control

Our Reboxetine Mesylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity pharmaceutical grade specifications, including identity, potency, and impurity profile. We provide full traceability and support regulatory submissions. Certificates of Analysis (COA) documenting compliance with in-house specifications are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.