Description

Dl-Tyrosine-β-13C CAS NO 93627-94-2 is a stable isotope-labeled analog of the amino acid tyrosine, where the beta carbon is enriched with carbon-13. This compound is a critical tool for advanced research and development, enabling precise metabolic pathway tracing and quantitative analysis in complex biological systems. It is essential for scientists and manufacturers in the pharmaceutical, biotechnology, and life science sectors who require high-fidelity internal standards for mass spectrometry, NMR spectroscopy, and metabolic flux studies.

Application

• Biomedical Research: Used as an internal standard for the accurate quantification of tyrosine and related metabolites in biological fluids and tissue samples via LC-MS/MS and GC-MS.
• Metabolic Studies: Enables precise tracing of carbon flux in metabolic pathways, crucial for research in cancer metabolism, neurotransmitter synthesis, and protein turnover.
• Pharmaceutical Development: Serves as a labeled precursor in the synthesis of isotopically labeled drug candidates for pharmacokinetic (PK) and absorption, distribution, metabolism, and excretion (ADME) studies.
• Nutritional Science: Employed in stable isotope tracer studies to investigate protein metabolism, amino acid requirements, and whole-body protein synthesis in clinical settings.
• Diagnostic Reagents: A key component in the formulation of calibration standards and quality control materials for in-vitro diagnostic (IVD) kits targeting amino acid disorders.
• Proteomics & Biomarker Discovery: Facilitates relative and absolute quantification (SILAC, AQUA) in proteomic workflows to identify and validate disease biomarkers.

Basic Information

Product Name	Dl-Tyrosine-β-13C
CAS No.	93627-94-2
Molecular Formula	C913CH11NO3
Molecular Weight	182.18 g/mol (for 13C1 labeled form)
Synonyms	DL-Tyrosine-β-13C; (RS)-2-Amino-3-(4-hydroxyphenyl)propionic acid-β-13C; Tyrosine-3-13C (ambiguous); 3-(4-Hydroxyphenyl)-DL-alanine-β-13C; (±)-Tyrosine-β-13C; DL-4-Hydroxyphenylalanine-β-13C; 13C Labeled DL-Tyrosine; Tyrosine (DL, β-13C)
EINECS	Contact for details

Quality Control

Our Dl-Tyrosine-β-13C is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity, isotopic enrichment, and absence of biological contaminants. Certificates of Analysis (COA) are provided, detailing results for key parameters including HPLC purity, isotopic enrichment (Atom % 13C), and specific tests for identity and impurities. We support compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure and labeling position
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (Atom % 13C)	≥ 99% on the β-carbon
Chemical Purity (Titration)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.