Description

Tazobactam is a potent and highly specific β-lactamase inhibitor used in combination with β-lactam antibiotics to combat resistant bacterial infections. Its primary value lies in restoring the efficacy of antibiotics like piperacillin against a broad spectrum of pathogens, including those producing extended-spectrum β-lactamases (ESBLs). This compound is essential for the pharmaceutical industry, specifically in the formulation of critical injectable antibacterial drugs for hospital use. Tazobactam CAS NO 93528-38-2 represents a key component in modern antimicrobial therapy, addressing the global challenge of antibiotic resistance.

Application

• Pharmaceutical Active Ingredient (API): Primary use as a β-lactamase inhibitor in fixed-dose combination injectable drugs, most notably with piperacillin.
• Antibiotic Potentiator: Extends the spectrum and enhances the effectiveness of penicillin and cephalosporin class antibiotics against resistant bacterial strains.
• Hospital Infection Treatment: Critical for formulating drugs used to treat complicated intra-abdominal infections, urinary tract infections, skin and skin structure infections, and nosocomial pneumonia.
• Research & Development: Used in microbiological and pharmacological studies to investigate bacterial resistance mechanisms and develop new combination therapies.
• Veterinary Medicine: Potential application in veterinary pharmaceuticals for treating bacterial infections in animals.
• Reference Standard: Serves as a high-purity analytical standard for quality control testing in pharmaceutical manufacturing and regulatory compliance.

Basic Information

Item	Details
Product Name	Tazobactam
CAS No.	93528-38-2
Molecular Formula	C10H12N4O5S
Molecular Weight	300.29 g/mol
Synonyms	(2S,3S,5R)-3-Methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide; YTR 830; Tazobactam Acid; CL 298,741; LK 157; Tazobactamum; TAZ; Zosyn component
EINECS	Contact for details

Quality Control

Our Tazobactam is manufactured under strict quality systems to meet the rigorous standards of the pharmaceutical industry. We provide material that complies with major pharmacopoeial specifications, including USP and EP monographs. Every batch undergoes comprehensive analytical testing, including assay, impurity profiling, residual solvent analysis, and microbiological examination. A Certificate of Analysis (COA) documenting all test results is provided with each shipment to ensure full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%
Heavy Metals	≤ 20 ppm
Microbial Limits	Conforms to EP/USP

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.