Description

Durlobactam Sodium Salt (Synonyms: Etx2514) CAS NO 1467157-21-6 is a potent and specific β-lactamase inhibitor designed to restore the efficacy of sulbactam against multi-drug resistant Acinetobacter baumannii. This compound is critical for pharmaceutical research and development targeting serious hospital-acquired infections. It is primarily required by pharmaceutical manufacturers, contract research organizations (CROs), and academic institutions engaged in the development of novel antibacterial combination therapies.

Application

• As a key active pharmaceutical ingredient (API) in the development of novel antibacterial combination drugs, specifically with sulbactam.
• For in-vitro and in-vivo pharmacological research to combat carbapenem-resistant Acinetobacter baumannii (CRAB) infections.
• Used in preclinical and clinical studies to evaluate pharmacokinetics, pharmacodynamics, and safety profiles of new antibiotic formulations.
• As a reference standard for analytical method development and quality control in pharmaceutical manufacturing.
• For microbiological research into the mechanisms of β-lactamase inhibition and bacterial resistance.

Basic Information

Product Name	Durlobactam Sodium Salt
CAS No.	1467157-21-6
Molecular Formula	C12H14N3NaO6S
Molecular Weight	351.31 g/mol
Synonyms	Etx2514; ETX2514; (2S,5R)-7-Oxo-6-(sulfoxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide, Sodium Salt; Durlobactam sodium; Sulbactam-Durlobactam component; β-lactamase inhibitor ETX2514; Sodium (2S,5R)-7-oxo-6-(sulfoxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide
EINECS	Contact for details

Quality Control

Our Durlobactam Sodium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-grade pharmaceutical standards. Certificates of Analysis (COA) with detailed chromatographic data are provided and available upon request to support your regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.