Description

Avibactam CAS NO 1192500-31-4 is a novel, non-β-lactam β-lactamase inhibitor of significant pharmaceutical importance. Its core value lies in its ability to restore the efficacy of β-lactam antibiotics against resistant bacterial strains, making it a critical component in the fight against antimicrobial resistance (AMR). This compound is essential for pharmaceutical manufacturers and research institutions developing next-generation combination antibiotic therapies, particularly for treating serious Gram-negative infections.

Application

• Active Pharmaceutical Ingredient (API) in fixed-dose combination antibiotics (e.g., with ceftazidime or aztreonam).
• Key intermediate in the synthesis of advanced β-lactamase inhibitor-based drugs.
• Research and development of novel antibacterial agents targeting multidrug-resistant pathogens.
• Reference standard for analytical testing and quality control in pharmaceutical laboratories.
• Biochemical research tool for studying β-lactamase enzyme mechanisms and inhibition.

Basic Information

Product Name	Avibactam
CAS No.	1192500-31-4
Molecular Formula	C7H11N3O6S
Molecular Weight	265.24 g/mol
Synonyms	NXL-104; AVE1330A; (2S,5R)-7-oxo-6-(sulfoxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; Avibactam Sodium; β-lactamase inhibitor NXL104; Diazabicyclooctane β-lactamase inhibitor
EINECS	Contact for details

Quality Control

Our Avibactam is manufactured under strict quality systems to meet the exacting standards of the pharmaceutical industry. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identification by IR and NMR, and stringent control of related substances and residual solvents. Certificates of Analysis (COA) compliant with cGMP guidelines are provided to ensure traceability and regulatory compliance for your drug development and manufacturing processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.