Description

S-Venlafaxine is the single enantiomer of the widely used serotonin-norepinephrine reuptake inhibitor (SNRI), offering a targeted pharmacological profile for advanced research and development. This high-purity intermediate is critical for synthesizing next-generation active pharmaceutical ingredients (APIs) with improved efficacy and reduced side-effect profiles. It is essential for pharmaceutical manufacturers and R&D laboratories focused on developing enantiomerically pure neuropsychiatric therapeutics and novel drug delivery systems.

Application

• Active Pharmaceutical Ingredient (API) Synthesis: Key chiral building block for the production of S-enantiomer specific venlafaxine and related SNRI pharmaceuticals.
• Pharmaceutical R&D: Used in preclinical and clinical studies to investigate the distinct pharmacokinetic and pharmacodynamic properties of the S-enantiomer.
• Reference Standard: Serves as a high-purity chemical reference standard (CRS) for analytical method development, validation, and quality control testing in regulatory submissions.
• Process Chemistry: Employed in the development and scale-up of asymmetric synthesis routes for complex chiral molecules.
• Metabolite Studies: Utilized in the synthesis and study of specific drug metabolites for toxicological and metabolic pathway analysis.

Basic Information

Product Name	S-Venlafaxine
CAS No.	93413-44-6
Molecular Formula	C17H27NO2
Molecular Weight	277.40 g/mol
Synonyms	(S)-Venlafaxine; (1S)-1-[2-(Dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol; (S)-1-[2-(Dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexan-1-ol; S-(-)-Venlafaxine; Levomilnacipran related compound; Pristiq impurity
EINECS	Contact for details

Quality Control

Our S-Venlafaxine CAS NO 93413-44-6 is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity assay and impurity profiling, to ensure it meets exacting standards for pharmaceutical research. A Certificate of Analysis (COA) detailing specific results for identity, purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.5%
Chiral Purity (Chiral HPLC)	≥ 99.0% (S-enantiomer)
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.