Description

Hemoglobin F La Grange is a specialized, high-purity form of fetal hemoglobin (HbF) isolated from the La Grange variant. This compound is essential for advanced biochemical research and diagnostic development, offering a critical reference standard for studying hemoglobinopathies and oxygen transport mechanisms. It is primarily utilized by research institutions, diagnostic kit manufacturers, and pharmaceutical companies engaged in hematology and therapeutic development.

Application

• Biochemical Research Standard: Serves as a purified reference material for studying the structure, function, and kinetics of fetal hemoglobin.
• Diagnostic Assay Development: Used as a critical component in the calibration and validation of diagnostic tests for sickle cell disease, β-thalassemia, and other hemoglobin disorders.
• Therapeutic Research: Employed in preclinical studies aimed at reactivating fetal hemoglobin production as a therapeutic strategy for hemoglobinopathies.
• Quality Control Reagent: Acts as a control standard in clinical laboratories to ensure the accuracy of hemoglobin electrophoresis and chromatography systems.
• Academic & Clinical Studies: Supports fundamental and applied research in physiology, pediatrics, and hematology at universities and medical centers.

Basic Information

Product Name	Hemoglobin F La Grange
CAS No.	93051-97-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	HbF La Grange; Fetal Hemoglobin La Grange; Hemoglobin F LaGrange Variant; γ-Globin Variant; HbF Variant; La Grange HbF; Glycosylated Fetal Hemoglobin (La Grange)
EINECS	Contact for details

Quality Control

Our Hemoglobin F La Grange is produced and handled under stringent quality protocols to ensure batch-to-batch consistency and purity suitable for research and diagnostic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and relevant biochemical parameters. We adhere to GLP (Good Laboratory Practice) standards in our analytical procedures to support the integrity of your research and development work.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This material is hygroscopic (moisture-sensitive); ensure the container is sealed under inert atmosphere or desiccant after each use to maintain stability. For long-term storage, consider freezing at -20°C or below.

Specification

Item	Specification
Appearance	Lyophilized powder
Identification (HPLC/Electrophoresis)	Conforms to HbF La Grange standard
Purity (HPLC)	≥ 95%
Protein Content (Biuret)	≥ 90%
Solubility	Soluble in buffer or water
Moisture Content (Karl Fischer)	≤ 5.0%
Biological Activity (Oxygen Binding)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.