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2-Hydroxyethyl-2-Deoxy-2-(3-Hydroxytetradecanamido)Glucopyranoside-4-Phosphate CAS NO 122351-28-4


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CAS No.:122351-28-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Hydroxyethyl-2-Deoxy-2-(3-Hydroxytetradecanamido)Glucopyranoside-4-Phosphate is a chemically defined, high-purity intermediate crucial for advanced biochemical research and pharmaceutical development. This compound matters as a key synthetic precursor for investigating and developing novel antibacterial agents and immunomodulators, particularly those targeting lipid A biosynthesis pathways. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors requiring precise, well-characterized building blocks for complex molecular synthesis.

Application

  • Pharmaceutical Intermediate: A critical precursor in the synthesis of complex lipid A analogs and other bioactive glycolipids for antibacterial drug discovery.
  • Biochemical Research: Used as a standard or substrate in enzymatic studies related to bacterial cell wall biosynthesis and endotoxin structure-activity relationships.
  • Immunology Studies: Employed in research to understand and modulate the immune response triggered by bacterial endotoxins (LPS).
  • Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
  • Glycoconjugate Synthesis: A building block for the chemical and enzymatic synthesis of complex carbohydrate-based molecules for vaccine development.

Basic Information

Product Name 2-Hydroxyethyl-2-Deoxy-2-(3-Hydroxytetradecanamido)Glucopyranoside-4-Phosphate
CAS No. 122351-28-4
Molecular Formula C23H44NO12P
Molecular Weight 557.57 g/mol
Synonyms 2-Deoxy-2-[(3R)-3-hydroxytetradecanamido]-3-O-[(R)-2-hydroxyethyl]-D-glucopyranose 4-(Dihydrogen Phosphate); Lipid X (Hydroxyethyl Derivative); 2-Hydroxyethyl Lipid X; 2-O-(2-Hydroxyethyl)-2-deoxy-2-[(3R)-3-hydroxytetradecanamido]-D-glucopyranose 4-phosphate; Glucosamine 4-phosphate derivative; Monophosphoryl Lipid A precursor analog
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Quality Control

Every batch of 2-Hydroxyethyl-2-Deoxy-2-(3-Hydroxytetradecanamido)Glucopyranoside-4-Phosphate is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with rigorous internal specifications suitable for research and development applications. A detailed Certificate of Analysis (COA) providing purity, identity, and impurity profile data is supplied with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Assay (HPLC) ≥ 95.0%
Water Content (KF) ≤ 5.0%
Heavy Metals ≤ 20 ppm
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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