Description

1,5-Anhydro-D-Glucitol is a stable, non-metabolizable glucose analog and a key biochemical marker. This compound is of significant commercial and research interest due to its role as a specific and sensitive indicator for short-term glycemic control. It is primarily utilized by manufacturers in the diagnostic, pharmaceutical, and life science research sectors for developing assays and studying carbohydrate metabolism.

Application

• Diagnostic Reagent Manufacturing: A critical raw material (reference standard) for the production of enzymatic assay kits used to measure 1,5-AG levels in serum, a recognized marker for monitoring short-term glycemic control in diabetes management.
• Pharmaceutical Research & Development: Used as a stable tracer or model compound in metabolic studies, drug discovery programs targeting glucose transporters, and research into diabetic complications.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies of glucosidases and other carbohydrate-processing enzymes to understand their mechanism and kinetics.
• Reference Standard: Employed as a high-purity calibrant and system suitability standard in analytical laboratories for HPLC, LC-MS, and other chromatographic methods to ensure assay accuracy and reproducibility.
• Nutritional Science Studies: Utilized in research investigating non-digestible carbohydrates, their interaction with gut microbiota, and potential metabolic effects.

Basic Information

Product Name	1,5-Anhydro-D-Glucitol
CAS No.	154-58-5
Molecular Formula	C6H12O5
Molecular Weight	164.16 g/mol
Synonyms	1,5-AG; 1,5-Anhydroglucitol; 1,5-Anhydro-D-sorbitol; 1-Deoxyglucose; D-Glucitol, 1,5-anhydro-; Anhydroglucitol; 1,5-AGlu; Statzyme® 1,5-AG (component)
EINECS	205-823-4

Quality Control

We supply 1,5-Anhydro-D-Glucitol in high-purity grades suitable for diagnostic and research applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each batch to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Specific Optical Rotation	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.